USE OF DIRECT ORAL ANTICOAGULANTS FOR THE PREVENTION AND TREATMENT OF THROMBOEMBOLIC DISEASE IN PATIENTS WITH REDUCED RENAL FUNCTION: A SHORT REVIEW OF THE CLINICAL EVIDENCE

Use of direct oral anticoagulants for the prevention and treatment of thromboembolic disease in patients with reduced renal function: a short review of the clinical evidence

Kristine C Willett, Amanda M Morrill Department of Pharmacy Practice, School of Pharmacy, MCPHS University, Manchester, NH, USA Background: The use of direct oral anticoagulants (DOACs) is restricted by the limitations Wooden Blocks of clinical trials guiding therapy for patients with renal impairment, as many of these trials excluded patients with

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